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Showing posts with label geneza pharmaceuticals. Show all posts
Showing posts with label geneza pharmaceuticals. Show all posts

Tuesday, February 10, 2015

Beginners Guide to Geneza Pharmaceuticals GP Sust 270 Cycle

There are a lot of questions about GP Sust 270 dosing. Due to sustanon's GP Sust 27 of esters, it is a little difficult to wrap your head around sometimes. Hopefully this will help clear up some of the confusion.

Sustanon is a Testosterone Blend. Each Lab has its own mix, but generally speaking it will contain 3 to 5 types of Test.
Below are several of the Test Esters that might be found in a sust blend and the half life of each:
Testosterone Acetate (1-3 Days)
Testosterone Propionate (3 Days)
Testosterone Phenylpropionate (3-5 Days)
Testosterone Isocaproate (7-10 Days)
Testosterone Decanoate (15-30 Days)

Geneza Pharmaceuticals GP Sust 270 has these amounts per mL:
20 mg/ml Testosterone Acetate
30 mg/ml Testosterone Propionate
60 mg/ml Testosterone Phenylpropionate
60mg/ml Testosterone Isocaproate
100mg/ml Testosterone Decanoate


Looking back quickly at the half life of the esters of test, you see that half of those used are fast releasing (around 3 days) and half are slow releasing (at least 10 days). Now before anything else is explained, let compare GP Sust 270 cycle to a Test Enanthate cycle with a Test Prop kickstart. Typically with a Test E cycle, you start to feel the test enanthate kick in sometime around the 5th week, so I will use week 5 as the Test E fully kicked in for my example.

Ok, so this Test E cycle will look like this:
Weeks 1-10 Test E @ 500mg/week
Weeks 1-5 Test P @ 150mg EOD (this totals 525mg/week)

It is clearly shown here that for weeks 1 to 5 we are taking a total of over 1gram of test. This is split into 500mg Test E which slowly pools for weeks, and 500mg of Test P which is used up within days. This should be fairly straight forward so far.

Onto the more complicated stuff now... What we are looking for in a cycle is a gradual build-up of test (for about the first week), followed by several weeks where we want to keep blood levels as steady as possible (usually 500mg/week of test), followed by a gradual coming-off of test (again, about a week of the test slowly leaving the body).
GP Sust 270 is an excellent drug to keep these blood levels steady if you inject it properly, and you only need to use 1 compound instead of 2 like in our Test E/P example. The tricky part is figuring out how much test is actually in the body with all these various esters in there.

For the first 5 weeks of GP Sust 270 cycle, the long esters are not present in numbers high enough to consider useful because they are still pooling. The only ones we need to worry about during this time are the fast esters. I will use GP Sust 270 for this cycle layout,
this consists of 110mg fast esters and 160mg slow esters.
So if we are looking for 500mg/week for these first 5 weeks (using EOD injections) we can easily do this by taking 1ml per injection.
4 x 110mg = 440mg/week. (**Note** the 4 is how many injections/week you get with EOD shots)

Weeks 1 - 5 GP Sust 270 - 1mL EOD

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As the longer esters begin to kick in, you can drop the dose. If at week 6 you drop to 500mg TOTAL test/week (since both fast and slow esters are both active at this point) we drop to a little under 2ml/week, which works out to 1/2mL EOD.
270mg * 1/2ml = 135mg * 4inj/week = ~540mg/week

Weeks 6-10 GP Sust 270 - .5mL EOD

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This is good enough, but if you want even better blood levels, you will need to taper down the test over the span of a few weeks when the slow esters begin to kick in.... lets say weeks 4-7. During this time we want between 1ml EOD and .5ml of test EOD....obviously this is .75ml EOD.
270mg * .75 = 202.5mg * 4 inj/week = ~810mg/week

Weeks 4-7 GP Sust 270 - .75mL EOD

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What does this all give us now?
Weeks 1 - 3 GP Sust 270 1mL EOD ( ~1080mg/week)
Weeks 4 - 7 GP Sust 270 .75mL EOD (~810mg/week)
Weeks 8-10+ GP Sust 270 .5mL EOD (~540mg/week)

Hopefully this is easy enough to understand. The 1grm/week of GP Sust 270 may look intimidating at first, but by now you should realize it is no different from what the Test E/Test P doses are.

Friday, January 31, 2014

GP T3 Trijodthyronin or Cytomel by Geneza Pharmaceuticals

GP T3 (Trijodthyronin, Cytomel) is a thyroid hormone designed and developed to treat hypothyroidism. Hypothyroidism is simply a condition where adequate thyroid hormone(s) are not being produced; commonly this can be caused by an iodine deficiency, as well as pituitary malfunction among other causes but it is a condition that is quite common. Through the use of GP T3 (Cytomel) we can increase the amount of thyroid hormones we have in our body, most notably the Triiodothyronine hormone commonly known as T3. The Triiodothyronine hormone is responsible for many functions, most notably metabolic activity but it also plays a role in bodily growth and the heart among many others. As T3 is produced by the pituitary gland its mode of action in terms of development and release is regulated by the thyroid-stimulating hormone (TSH.) Once thyroid hormones both T3 and T4 reach a certain level in the blood production is decreased as increased levels block TSH from being released; however, once the levels fall TSH is again released and more T3 and T4 is produced. By supplementing with GP T3 (Cytomel) we actively increase the amount of T3 in our body far beyond what natural TSH will allow.

The Benefits of GP T3
With a simple understanding of T3 hormone its benefits should come quite easily. By taking Cytomel we increase the amount of T3 in our body, by increasing the amount of T3 in our body we increase metabolic activity; by increasing metabolic activity we increase the rate in-which we burn fat. When we look at it in its most simplistic terms it is just that, rather simple; however, to fully understand the benefits of Cytomel we must understand the full effects of the T3 hormone which are quite vast and affect many various areas. While these affects are vast we are only largely concerned with how they affect metabolic activity; however, it’s effects can stretch to even the heart as increased levels of the T3 hormone increase cardiac output

By taking GP T3 (Cytomel) we greatly increase protein efficiency; however, we also increase the rate in-which protein is broken down. Due to this fact adequate amounts of protein must be taken in but this is good news as even though we require more than normal each gram is now being utilized to a far greater degree. Further and this is of the greatest importance, when we take Cytomel we increase the rate in-which glucose is metabolized by increasing the rate in-which glycogen is broken down. The faster this occurs the sooner the body is required to rely on stored body-fat for an energy source. Further and of equal importance, by taking Cytomel we increase the rate in-which cholesterol is broken down; all of these things greatly aid in increasing the rate of lipolysis.

The Side-Effects of GP T3 (Cytomel)
As is with all medications GP T3 (Cytomel) does carry with it potential negative side-effects, however many of the side-effects commonly associated with this medication are of little truth but some do exist. The blatant obvious negative effect is undoubtedly the loss of muscle tissue; as many performance enhancing athletes use GP T3 (Cytomel) in an aid to lose body-fat they do so on a calorie restricted diet, because of this low consumption of calories, if adequate amounts are not in place muscle tissue will be burned. For this reason, a performance enhancing athlete will never take GP T3 without anabolic steroids, ignoring this rule will assuredly result in the loss of a vast amount of lean tissue. Beyond this possible negative side-effect others do exist but they prove to be very individualistic, dose dependent and in many cases very rare. Possible side-effects include most commonly, headaches, insomnia and excess sweating. Many women who use Cytomel may also find their menstrual cycles disrupted, however, this is often to be expected when body-fat becomes extremely low.

The GP T3 (Cytomel) Myths
A common myth revolving GP T3 (Cytomel) is that it will damage your thyroid production beyond repair and while it is possible for this myth to hold a small amount of truth it is generally far exaggerated and borne of fear. While extreme Cytomel use for an extreme amount of time may have a damaging effect there is no hard proof, however, we do know that Cytomel can be used for decent lengths of time, up to nearly a year with no permanent damage being done to the thyroid. However, most will never find a need to use any thyroid medication for this extended period of time unless they already suffer from some level of permanent thyroid damage. Nevertheless, make no mistake, the use of GP T3 (Cytomel) will prevent your thyroid from producing its own natural T3 hormone but it will recover full capabilities in most all cases in a mere 2-3 months once use is discontinued and often sooner in some individuals.

GP T3 (Cytomel) Doses & Cycles
We have established that as a performance enhancing athlete GP T3 (Cytomel) is to only be used in conjunction with anabolic steroids and never alone as use alone will in-fact result in a loss of muscle tissue. With this in mind the next question is when is the best time to use? It should go without saying that during cutting cycles such as a competitive bodybuilding cycle is the best time to use this medication and common practice is to use GP T3 (Cytomel) the final 6 weeks of competition to get rid of that last bit of fat; however, it can be successfully used for the entire duration of a diet but one will need to keep an eye on tissue loss if this path is taken. For most a cycle of GP T3 that is in the 6-8 week range will prove to be all the GP T3 (Cytomel) they’ll ever need. As for the amounts, generally 25mcg per day is a good place to start with increases of 12.5mcg being applied as needed. This protocol includes GP T3 cycles for both men and women; however both will necessarily keep the dose as low as possible and only increase as needed. Most men can increase their dose safely to 150mcg per day while women will necessarily keep a maximum dose at 100mcg per day. In either case, learn to listen to your body, learn how to accurately observe your body and the effects and if you do you’ll find your GP T3 use to be more enjoyable and effective. There is a final note that will prove to provide a great benefit in thyroid recovery after use is discontinued; easing into recovery is far more beneficial than a cold turkey stop. There is no need to gradually ramp down but rather simply drop your dose down to the original starting point of 25mcg every day and hold for approximately two weeks. By following this method you will ensure your thyroid begins production sooner than later.

Monday, November 25, 2013

How To Prevent Estrogen Effects with GP Anastrozole by Geneza Pharmaceuticals

GP Anastrozole is an oral aromatase inhibitor manufactured by Geneza Pharmaceuticals. It was created for adjutant therapy of postmenopausal women with hormone receptor-positive early breast cancer. GP Anastrozole is a true aromatase inhibitor which works by blocking the aromatase enzyme in the body, thus limiting the amount of estrogen buildup that takes place.

Another use of anastrozole for men is to maintain a powerfully-built and bulky physique among bodybuilders, especially those who take anabolic steroids. One function of steroids is that it mimics the actions of naturally occurring testosterone, resulting in the increase of protein levels, muscle buildup, and strength improvement. Ironically, the excessive levels of testosterone and testosterone-like drugs signal the body to convert the male hormones into estradiol, which can lead to development of female features such as breasts and fat retention. Bodybuilders counter this hormone conversion by using anastrozole, but usage is often mishandled and may produce more adverse effects.

In studies that have been done, Anastrozole has been shown to reduce estrogen in the body by roughly 50%. This is a good balance for bodybuilders, because some estrogen is needed in order for the full anabolic benefits of the steroids being taken to be achieved.

It is wrong to think, however, that estrogen and its effects (particularly water and fat retention) are absolutely detrimental to bodybuilding. Remember that this hormone is also responsible for muscle strength and gains. Consequently, it minimizes the occurrence of injury as it improves the ability of muscle fibers to withstand contractile tension or stress. Notice that one of the side effects of Anastrozole use is the likely occurrence of fractures, a major drawback of this drug. This is because when Anastrozole effectively blocks the formation of estrogen, it effectively blocks the benefits of this hormone as well. This is why many still decide for estrogen receptor antagonists like Nolvadex and Clomid because these drugs allow some estrogen activity in the body.

Further, aromatase inhibitors like Anastrozole have the tendency to completely suppressed estrogen activity, including its positive effect on cholesterol levels in the body. Anastrozole is known to decrease HDL what is commonly known as the 'good' cholesterol. Typically, bodybuilders using GP Anastrozole will begin taking it the day they start their cycle, and will run it throughout the duration of steroid administration. It is also important to point out GP Anastrozole's ability to increase testosterone in the body. Some studies have shown that natural testosterone levels have increases as much as 60% after the use of this substance for 7 days. Because of this, bodybuilders find this drug extremely effective during PCT where as they are trying to elevate natural levels as much as possible in order to avoid a post cycle "crash".

Daily dosage for males is from 0.5mg to 3mg. For women, a maximum dosage of 1mg per day is enough to combat estrogenic side effects. Because Anastrozole has a short active life, dosages are usually taken two to six times a day at equal intervals. During PCT, athletes normally start with higher dosage then implement a progressive decrease in dosage. The PCT protocol typically runs for seven to 14 days. In clinical studies, it has been observed that a daily dose of 1 mg of this drug results to more than 80% of estrogen suppression.

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