GenezaMeds.com

GenezaMeds.com

Friday, March 28, 2014

Boldenone Use and Cycles

The use of boldenone is gradually becoming more respected by many top athletes, and more than just for its appetite-enhancing properties. I suspect that in previous years bodybuilders have not found boldenone use as beneficial due to the preparations available to them. One popular brand of boldenone undecylenate is Ganabol; a vetinary preparation of boldenone has just 50mg per 1ml of oil carrier. Even a modest dose of 400mg per week would necessitate the administration of 8ml of oil which, bearing in mind the user will probably also be cycling other steroids, a real inconvenience. It is this author's view that a minimum of 600mg/week of boldenone undecylenate is needed for beneficial effects, ideally 800-1000mg/week. With preparations such as Ganabol, doses of 800-1000mg/week would require 16-20ml per week, which is not very practical.

Given the mild nature of boldenone, one should not expect dramatic gains. One may compare the gains from boldenone to that of methenolone (primobolan) for example, in that the gains are slow and steady, however generally quite retainable post-cycle. As there is little aromatisation, little water weight will be put on, so many may be disheartened at the beginning of a cycle when compared to an AS such as testosterone, which will put on several pounds of water in the first week. However one must remember that this water will be lost post-cycle, and if one can gain 1lb of muscle per week then little more can be asked of any AS. Given the relatively long half-life of the undecylenate ester (at least 8 days) and the mild nature of boldenone, it is best taken for a minimum of 10-12 weeks. Users do tend to suggest that the drug is best utilised in longer cycles. PCT should begin approximately 3-4 weeks after the last shot of boldenone undecylenate. Although many people claim boldenone is useful for cutting given its low aromatisation rates and increasing vascularity, the amplification of appetite is a negative aspect for cutting. Thus it is my opinion that the best use of boldenone is as part of a bulking cycle. This use gets the most out of boldenone's benefits – namely increased appetite.

Alternatively boldenone could be stacked with other non-aromatising drugs such as primobolan (methenolone) or masteron (drostanolone) where the small amount of estrogen produced by boldenone is beneficial and the resultant gains should be lean and more easily kept. Given the long undecylenate ester (11 carbons) normally attached to boldenone, injecting the hormone twice a week is more than sufficient, although favourable for stable blood levels over injecting once per week. If one purely wants to use boldenone for its appetite enhancing properties, lower doses of 400mg/week should suffice for this purpose, although the full benefit of boldenone in my opinion is not achieved at these lower doses. Some example cycles are outlined below (I recommend in all cases 500IUs HCG is administered weekly from week 1 throughout the cycle as this will significantly aid recovery by helping to stop shut-down from fully occurring):

Novice Mass Cycle
500mg Testosterone Enanthate/Cypionate pw, weeks 1-12
600mg Boldenone Undecylenate pw, weeks 1-11
Dianabol 30mg ed weeks 1-4 (alternatively the injectables can be doubled in the first week for a front-load)
PCT – 3 weeks after last testosterone injection

Low-aromatising Mass Cycle
800mg Boldenone Undecylenate pw, weeks 1-12
600mg Primobolan (Methenolone Enanthate) pw, weeks 1-13
(Optional – Anavar 60mg ed, weeks 1-16)
PCT – 3 weeks after last Primobolan injection

Advanced Mass Cycle (For very experienced users – recommend regular bloodwork before, during and after such a cycle)
500IUs HCG pw, weeks 1-18
1000-1500mg Testosterone Enanthate/Cypionate/Sust pw, weeks 1-16
500-750mg Deca (Nandrolone Decanoate) pw, weeks 1-14
800-1000mg Boldenone Undecylenate pw, weeks 1-14
150-200mg NPP (Nandrolone Phenylpropionate) eod, weeks 14-18
150-200mg Testosterone Propionate eod, weeks 16-18
100-150mg Trenbolone Acetate eod, weeks 12-18
(Optional kick-start with 40-50mg dianabol ed weeks 1-4)
PCT – 3 days after last Trenbolone Acetate injection

Thursday, March 13, 2014

Fat Loss Steroids

Quite often anabolic androgenic steroids are placed in two classes; bulking steroids or fat loss steroids/cutting steroids. While either phrase largely implies the desire behind anabolic use it can often at times be a bit inaccurate. The fact of the matter is very simple, most anabolic steroids can achieve either purpose; while the primary purpose of many steroids can vary, most possess a level of both qualities including body fat reduction; varying to a degree. For example, there are certain steroids that are far better served for adding mass, steroids that are far better served for increasing strength or performance. The same can be applied to fat loss steroids; while anabolic androgenic steroids do not carry with them the primary purpose of burning fat some will do so in a secondary fashion to a higher degree. What we’ve done here is listed some of the most common questions, myths and often confused ideas and followed it with the absolute truth. By following this list you will have a much better understanding of the concept of fat burning steroids.

One of the most common reasons anyone uses anabolic androgenic steroids is for the purpose of leaning out and cutting up. With this being a common primary purpose there is a strong desire to ensure you’re using the best fat loss steroids available. Not only are the introduction to fat loss steroids important to you in achieving this purpose but so are the performance enhancing drugs (PED’s) you will add in addition.

Let’s be very clear on one important factor regarding anabolic androgenic steroids; while they may possess fat burning qualities none of them serve this primary purpose therefor none of them can be labeled fat loss steroids in a primary sense. Anabolic androgenic steroids largely serve four general primary purposes:

    Increasing Strength
    Increasing Muscle Mass
    Increasing Athletic Performance
    Increasing the “Hardness” of a Physique

While these are the primary purposes they will vary to a degree from one steroid to the next; some steroids serve one purpose more than another while others serve an entirely different primary function. Even so, a secondary characteristic of many can be fat burning and thereby it is these we may generally label fat loss steroids.

Increasing Fat Loss Steroids Abilities

While the primary purpose is not fat loss but a secondary function, additional non-steroidal drugs can greatly benefit and add to this effect. Of those belonging to the hormone class, without question the best hormone we can add as well as the best PED of all to serve this purpose is Human Growth Hormone (HGH.) Not only can HGH greatly increase fat burning but it can further make the steroids we use more effective including their secondary traits.

Other commonly used PED’s used in this purpose most largely include Clenbuterol (Clen) and Cytomel (T3.) While neither is a steroidal drug, the former being a bronchial medication and the latter a thyroid medication both can be positive additions to a cutting cycle and increase the amounts of fat lost. While neither of these will change the structure of function of the steroids used, in a sense, due to the mode of actions by each PED being used, including the steroids, by this mode of action when coupled together, our anabolics become stronger fat loss steroids.
How to Stack Fat Loss Steroids

In most cases you will need to build your cycle around testosterone; not only is testosterone an important part of most cycles it is all-around the most efficient and effective steroid known to man. Beyond testosterone there are many additional items we can add that may more or less fall into the fat loss steroids camp. Steroids such as Trenbolone and Stanozolol are always top choices, as can be Equipoise and Anavar. Beyond the steroids, effective fat burners as mentioned above are always a helpful tool in addition; cycles and stacks with these items, in conjunction with solid anabolic androgenic steroids and HGH will prove to be the ultimate fat burning machines.

Q: What are the best fat burning steroids?

A: While the primary purpose does not revolve around body fat reduction, Trenbolone is without question the king of fat loss steroids available today. Partially due to its incredible nutrient partitioning capabilities and its androgen binding abilities Trenbolone can greatly increase the rate in-which adipose tissue is reduced. While any form of Trenbolone will generally achieve this purpose, most will find Tren-A or Trenbolone-Acetate to be the most efficient and effective.

Q: Can fat loss steroids be used successfully in a bulking cycle?

A: Absolutely and for good reason; anabolic androgenic steroids are not classified as fat burners and non-fat burners. While they may possess this trait it is often a secondary characteristic. Our example of Trenbolone is a perfect example, as are the steroids Stanozolol and Equipoise. While the first possess the ability of all traits, increasing mass, strength, hardness and fat loss abilities, the latter two possess the same without as much mass increasing properties. However, all three of these steroids can be used successfully in a bulking cycle and should never be labeled as cutters only.

Q: Can Dianabol & Anadrol be used as fat loss steroids?

A: The common belief is that neither Dianabol or Anadrol can be used in a cutting cycle and are only to be used during off-season, bulking or gaining phases; however, the truth is far from this way of thinking. There is no doubt about it, both of these steroids serve the primary purpose of adding muscle mass and both can greatly increase strength but make no mistake, both can be effectively used in a cutting cycle; in most cases this will be applied to competitive bodybuilders. However, the question remains; will they burn fat? While this is not their primary purpose by any means and we will not label either as fat loss steroid both can have a positive effect on body fat reduction. If for no other reason, when we increase our lean tissue we create a field that burns more fat; the more lean mass the greater the fat burning properties available.

Q: What is the most effective and safe fat loss steroid?

A: While fat loss is far from its primary purpose the steroid Anavar can achieve this in a secondary fashion. Not only does Anavar fall into the fat loss steroids category it is by far the safest anabolic androgenic steroid available and is largely free from any of the nasty side-effects commonly associated with steroid use.

Q: Should I avoid testosterone if trying to lean out?

A: This is perhaps the most misunderstood question of all and much of the urban legend surrounding testosterone as it pertains to this topic is nothing short of the worst advice you’ll ever hear. The truth is simple; most all anabolic steroid cycles should include testosterone. Not only is testosterone generally well-tolerated by most who use it, it is further imperative for proper bodily function as well as increasing or maintaining muscle tissue. In an all-around sense, testosterone is the best anabolic androgenic steroid available to any healthy male adult and while the many forms of testosterone are not fat loss steroids in primary function, their primary functions will lead to a leaner physique; much leaner than if it were not used.
The Bottom Line

There are literally hundreds of options we have when we consider how to stack, what to stack and how best to mix and match ourfat loss steroids with other fat burning tools. Regardless of the options we choose safety will always be our paramount concern. While fat loss steroids can be very useful and effective it is easier to run into problems when cutting when responsible use is not applied. In most cases it is a case of over eagerness, a desire to speed up the results. As are most things in life and this applies heavily to steroid use, display patience and discipline; your results and overall health will thank you in the end.

Wednesday, March 5, 2014

The Benefits of Human Growth Hormone

To understand the benefits of Human Growth Hormone we can largely see them by simply understanding its basic function(s) as discussed above; however, unfortunately as we age such benefits began to fall short as natural HGH production declines as we age and often at a rapid rate. For this reason more and more people the world over, both men and women have begun supplementing with biosynthetic Human Growth Hormone in an effort to avoid such a crash, as well as many athletes from baseball to football, track & field to bodybuilders and power lifters, gym rats and everything in-between. While therapeutic doses aimed at slowing down the signs of aging are common, as it pertains to the athletic world and performance enhancing doses are commonly much higher as the idea here is not to simply provide adequate levels but to surpass them so that the benefits can become further enhanced.

Through the use of supplemental Human Growth Hormone the individual can expect to reap the rewards of several beneficial applications and they apply universally to all who use it regardless of purpose; however, the rate of acceleration and the total end will largely vary from one to the next based on dosing and the coupling of anabolic androgenic steroids. Anabolic steroid use is very common with HGH use in the athletic world as both act in a means to work together enhancing the effects of each.

Those who administer biosynthetic HGH can largely expect a host of beneficial attributes such as muscle tissue growth, higher metabolic rates, a leaner and tighter physique, increased recovery within the body, increased bone, joint and tendon strength, healthier looking skin, as well as increased energy. While these are largely the physical attributes in their general sense, Human Growth Hormone goes far beyond the direct physical and holds other very important traits as well. Those who supplement with Human Growth Hormone will find they possess a greater clarity of thought and focus as well as enhanced moods overall as HGH can largely stave off such problems as depression. If levels of HGH in the body fall below optimal range each one of the positive benefits just discussed begins to decline as well; this is why as you can see proper levels are very important. In that same light, as levels increase beyond natural production each and every beneficial attribute is enhanced to degrees previously deemed unimaginable.

The Side-Effects of Human Growth Hormone (HGH):

Human Growth Hormone is without question among the safest hormones we can use in supplemental form and is largely more than well-tolerated by both men and women, even in large doses beyond simple therapeutic levels. However, as is with all hormone supplementation, all medications of all forms negative and adverse side-effects do exist but in responsible users they are not only avoidable but largely non-existent. Those who are obtaining therapeutic level doses will find side-effects rarely occur but such side-effects as bone growth in the hands, feet and jaw, carpal tunnel and slight water retention or bloat can occur in some. Most who use HGH for performance purposes, as the dose will be higher than therapeutic form many will notice a tingling feeling in the hands in feet, especially when use first begins and the body adapts. Beyond these possible but rare effects, when used responsibly, as you can see this is by far the safest hormone of all hormones in-which we can supplement with.

Real Human Growth Hormone:

As is common in the world of anabolic steroids, as HGH is not an anabolic steroid in any shape or form, like many steroids it is often counterfeited, so much so it is without question the most commonly counterfeited hormone in the performance enhancing world when purchased on the black market. Moreover, in recent years due to HGH popularity increasing many legal peptide fragments have hit the shelves; these fragments are often a partial Human Growth Hormone medication but this is like buying half a sandwich and one that won’t digest properly. While these fragment peptides are generally safe they are also generally worthless. When you are looking to obtain true blue Human Growth Hormone stay away from the generic black market brands and stick with true manufactures of the hormone such as Humatrope, Saizen, Serostim and Nutropin to name a few.

Human Growth Hormone Cycles and Doses:

Because it possesses such a high safety rating Human Growth Hormone can be used indefinitely; there is no max time frame in-which we must hold to. However, as beneficial as the hormone is it will take a long time to see such benefits; a few weeks of HGH therapy is a waste of money and a complete waste of good HGH. To reap a true benefit 16 weeks is generally the minimal amount of time you’ll want to supplement with HGH with 6 months being far more optimal. While this can be expensive consider this; the effects of Human Growth Hormone are largely permanent and that is worth noting.

Thursday, February 13, 2014

Testosterone C250 Testosterone Cypionate by Biomex Labs Cycles & Doses

Testosterone is a hormone naturally produced by both men and women responsible for a host of functions; most notably muscle and bone growth, regeneration and male sexual characteristics. While men produce nearly ten times as much testosterone as women both require adequate amounts of this androgen class hormone in order to maintain a proper endocrine system. For those who suffer from low levels of testosterone, as Testosterone C250 (Testosterone Cypionate) by Biomex Labs is a pure form of testosterone it is often used to combat this condition and return levels to a more suitable level. Those who suffer from low testosterone levels commonly find their libido to be reduced, fat gain and muscle loss to occur, as well as immune system deficiencies and even depression. As you can easily see testosterone is a very important hormone and with its many functions, when we increase levels beyond a normal range, as is the purposes in performance enhancing we effectively increase the attributes associated with this powerful anabolic androgenic steroid.

Testosterone C250 (Testosterone Cypionate) is truly a perfect anabolic steroid for any purpose; be it hormone replacement therapy (HRT), performance enhancing, bulking or cutting purposes it is a fine choice in all events. While 200mg every 7-10 days is common among HRT patients the dosing among performance enhancers will vary. 400mg-500mg per week split into two even doses is generally the rule of thumb for any beginner and quite commonly the max many will ever use or need. While we can safely use 1,000mg per week the risks will increase but such dosing is common in bodybuilding and power lifting circles and even beyond. An interesting note, while injections of 1-2 times per week is all that is needed, in recent years many competitive bodybuilders have begun injecting long ester based testosterones every other day, including Testosterone C250. The idea is to keep blood test levels at their peak max and while this would prove to be unnecessary on paper many bodybuilders report a more stable feeling by following this protocol; remember, what’s on paper does not always match up with real life.

As for your Testosterone C250 cycle, most will find 8 weeks of use to be the bear minimum with 16 weeks being far more efficient. Regardless of your duration of use a solid post cycle therapy (PCT) plan must be in place. Because Testosterone C250 (Testosterone Cypionate) is a long ester based testosterone you will necessarily begin PCT 3 weeks after your final injection, which may include hCG, Nolva and/or Clomid. Those who use hCG are advised to begin use approximately ten days before Nolva/Comid for approximately ten days of use.

Myth: Testosterone Cypionate is stronger than Testosterone Enanthate.
Truth: This is not only a myth but when you really stop and look it’s absolutely ridiculous. These two compounds are almost identical in every single way; milligram for milligram there is zero difference in-terms of power, potency, efficiency or effectiveness. The only significant difference between the two testosterone forms is in the half-life each carries but even then it’s really not significant in an applicable way at all. Testosterone-Enanthate carries a half-life of approximately 11 days while Testosterone C250 Testosterone Cypionate carries a half-life of approximately 12 days. If you understand steroids even in the slightest then you understand this difference is for all intense purposes meaningless.

Myth: Testosterone Cypionate will cause serious bloat and should not be used when cutting/dieting.
Truth: All testosterone forms can cause water retention, even Testosterone-Propionate, known by many to be a little easier regarding water. Testosterone, regardless of the form you use can convert to estrogen through aromatase and lead to estrogenic related side-effects, one of which is water retention. However, if we use a good aromatase inhibitor we can greatly alleviate this problem, although your individual sensitivity will vary from person to person. Here’s the kicker, all testosterones can lead to water retention; however, testosterone is the best steroid we can ever use for any cycle. The problem is most guys will use Testosterone Cypionate when “bulking” eat more carbohydrates than they have any business eating, bloat and blame it on the Testosterone Cypionate. Then when it’s time to diet they’ll use Testosterone-Propionate, eat far less carbohydrates, not bloat and start labeling these two testosterones inappropriately. Yes, you can absolutely use Testosterone Cypionate while dieting and end up ripped to the bone, in-fact, if your diet is on point we guarantee this will happen.

Myth: A low dose of Testosterone Cypionate will not produce any results.
Truth: Again, this is an outright lie; a mere 200mg of Testosterone Cypionate every 7-10 days can be life changing and give a boost to a physique it could have never found without. The problem is most use garbage; they buy their Testosterone Cypionate from underground labs that make their gear who knows where and nine times out of ten far below optimum potency and sanitary levels. It doesn’t matter who you are, if you take 200mg of Testosterone Cypionate per week in human grade form you will fill it, you will see results and benefits. Can you take more? Absolutely, 400-750mg per week is very common place; in competitive bodybuilding we often get as high as 1,000mg or more per week. However, the higher the dose the greater the risk but the greater the risk the greater the reward; it is a tradeoff the same as most things in life.

Friday, January 31, 2014

GP T3 Trijodthyronin or Cytomel by Geneza Pharmaceuticals

GP T3 (Trijodthyronin, Cytomel) is a thyroid hormone designed and developed to treat hypothyroidism. Hypothyroidism is simply a condition where adequate thyroid hormone(s) are not being produced; commonly this can be caused by an iodine deficiency, as well as pituitary malfunction among other causes but it is a condition that is quite common. Through the use of GP T3 (Cytomel) we can increase the amount of thyroid hormones we have in our body, most notably the Triiodothyronine hormone commonly known as T3. The Triiodothyronine hormone is responsible for many functions, most notably metabolic activity but it also plays a role in bodily growth and the heart among many others. As T3 is produced by the pituitary gland its mode of action in terms of development and release is regulated by the thyroid-stimulating hormone (TSH.) Once thyroid hormones both T3 and T4 reach a certain level in the blood production is decreased as increased levels block TSH from being released; however, once the levels fall TSH is again released and more T3 and T4 is produced. By supplementing with GP T3 (Cytomel) we actively increase the amount of T3 in our body far beyond what natural TSH will allow.

The Benefits of GP T3
With a simple understanding of T3 hormone its benefits should come quite easily. By taking Cytomel we increase the amount of T3 in our body, by increasing the amount of T3 in our body we increase metabolic activity; by increasing metabolic activity we increase the rate in-which we burn fat. When we look at it in its most simplistic terms it is just that, rather simple; however, to fully understand the benefits of Cytomel we must understand the full effects of the T3 hormone which are quite vast and affect many various areas. While these affects are vast we are only largely concerned with how they affect metabolic activity; however, it’s effects can stretch to even the heart as increased levels of the T3 hormone increase cardiac output

By taking GP T3 (Cytomel) we greatly increase protein efficiency; however, we also increase the rate in-which protein is broken down. Due to this fact adequate amounts of protein must be taken in but this is good news as even though we require more than normal each gram is now being utilized to a far greater degree. Further and this is of the greatest importance, when we take Cytomel we increase the rate in-which glucose is metabolized by increasing the rate in-which glycogen is broken down. The faster this occurs the sooner the body is required to rely on stored body-fat for an energy source. Further and of equal importance, by taking Cytomel we increase the rate in-which cholesterol is broken down; all of these things greatly aid in increasing the rate of lipolysis.

The Side-Effects of GP T3 (Cytomel)
As is with all medications GP T3 (Cytomel) does carry with it potential negative side-effects, however many of the side-effects commonly associated with this medication are of little truth but some do exist. The blatant obvious negative effect is undoubtedly the loss of muscle tissue; as many performance enhancing athletes use GP T3 (Cytomel) in an aid to lose body-fat they do so on a calorie restricted diet, because of this low consumption of calories, if adequate amounts are not in place muscle tissue will be burned. For this reason, a performance enhancing athlete will never take GP T3 without anabolic steroids, ignoring this rule will assuredly result in the loss of a vast amount of lean tissue. Beyond this possible negative side-effect others do exist but they prove to be very individualistic, dose dependent and in many cases very rare. Possible side-effects include most commonly, headaches, insomnia and excess sweating. Many women who use Cytomel may also find their menstrual cycles disrupted, however, this is often to be expected when body-fat becomes extremely low.

The GP T3 (Cytomel) Myths
A common myth revolving GP T3 (Cytomel) is that it will damage your thyroid production beyond repair and while it is possible for this myth to hold a small amount of truth it is generally far exaggerated and borne of fear. While extreme Cytomel use for an extreme amount of time may have a damaging effect there is no hard proof, however, we do know that Cytomel can be used for decent lengths of time, up to nearly a year with no permanent damage being done to the thyroid. However, most will never find a need to use any thyroid medication for this extended period of time unless they already suffer from some level of permanent thyroid damage. Nevertheless, make no mistake, the use of GP T3 (Cytomel) will prevent your thyroid from producing its own natural T3 hormone but it will recover full capabilities in most all cases in a mere 2-3 months once use is discontinued and often sooner in some individuals.

GP T3 (Cytomel) Doses & Cycles
We have established that as a performance enhancing athlete GP T3 (Cytomel) is to only be used in conjunction with anabolic steroids and never alone as use alone will in-fact result in a loss of muscle tissue. With this in mind the next question is when is the best time to use? It should go without saying that during cutting cycles such as a competitive bodybuilding cycle is the best time to use this medication and common practice is to use GP T3 (Cytomel) the final 6 weeks of competition to get rid of that last bit of fat; however, it can be successfully used for the entire duration of a diet but one will need to keep an eye on tissue loss if this path is taken. For most a cycle of GP T3 that is in the 6-8 week range will prove to be all the GP T3 (Cytomel) they’ll ever need. As for the amounts, generally 25mcg per day is a good place to start with increases of 12.5mcg being applied as needed. This protocol includes GP T3 cycles for both men and women; however both will necessarily keep the dose as low as possible and only increase as needed. Most men can increase their dose safely to 150mcg per day while women will necessarily keep a maximum dose at 100mcg per day. In either case, learn to listen to your body, learn how to accurately observe your body and the effects and if you do you’ll find your GP T3 use to be more enjoyable and effective. There is a final note that will prove to provide a great benefit in thyroid recovery after use is discontinued; easing into recovery is far more beneficial than a cold turkey stop. There is no need to gradually ramp down but rather simply drop your dose down to the original starting point of 25mcg every day and hold for approximately two weeks. By following this method you will ensure your thyroid begins production sooner than later.

Tuesday, January 21, 2014

Five things you didn’t know about peptides

Used by amateur athletes the new generation of performance and image enhancing peptides have rapidly grown in familiarity over recent months, but how much do you really know about them?

As the “drugs in sports” debate continues, we take one step back from the scandal to answer the core questions in an effort to correct the common misconceptions about peptides and their general use.

What are peptides?

Essentially, peptides are just very short proteins. Unlike the majority of proteins that provide the building blocks for cells or get chewed up for energy, a select few of these peptides actually “communicate” with cells and act as hormones.

Peptide hormones, like all other hormones, travel through the blood stream to all corners of the body. Many peptides are inert and do practically nothing; some interact with very specific tissues in the body (like the brain and your skin) and only a small handful have metabolic, image and/or performance enhancing effects.

A popular group known as growth hormone releasing peptides (or GHRPs) are examples of hormones that tell the body to produce more natural growth hormone, helping men and women to essentially gain muscle and lose fat. Different variations of peptide hormones have theoretical side-effects, like increased appetite, but very few have been legitimately researched in any form in human clinical trial.

According to a recent report by the Australian Crime Commission (ACC), the market for performance and image enhancing drugs (PIEDs) in Australia is large and diverse extending across a broad cross-section of the community.

With this widespread use of PIEDs across Australia, it’s important that some very key questions are asked and addressed. Below are what I consider to be the five most common and incorrectly answered questions.

One. Are peptides “anabolic steroids”?

Regardless of what you may have heard in the locker room, peptides are not anabolic steroids. Peptides are made up of amino acids just like any other protein. Steroids (anabolic/contraceptive/anti-inflammatory) are hormones too but it’s practically just a coincidence that a very small group of peptides causes anabolic effects like “anabolic steroids” do. The associated risk in peptide therapies is the orised to be much lower than that of testosterone-derived (anabolic) steroids however no injections are ever without risk.

Two. Are peptides illegal?

Although you won’t find many peptide hormones on the TGA’s current Poisons Schedule (where steroids and other illicit drugs of abuse are listed) peptides are slowly being added to this growing list with each periodical instalment. Depending on where they eventually land on the list, some are prohibited to be sold without prescription whilst others are illegal to have in possession at all.

Up until early February this year, peptide hormones and other performance-enhancing drugs were freely available to anyone with an internet connection and a credit card. The TGA has now moved to prevent the supply of these hormones online without a prescription.

Peptide use in sports is another issue altogether. Most peptide hormones have been explicitly blacklisted by the World Anti-Doping Authority (WADA) and are absolutely prohibited in numerous sporting codes. This is where the media has focused their attention and why a dark shadow has been cast across many sports both in Australia and overseas.

Three. Are all peptides performance-enhancing drugs?

Some peptide hormones can improve athletic performance. Performance-enhancing drugs (PEDs) can take many forms. Any compound which improves an athlete’s ability to outperform his or her competitors in an unfair manner technically falls under this umbrella term. A weight-loss drug can help a MMA fighter unfairly improve body composition before weigh-ins just like stimulants can improve a sprinter’s split.

Not all peptide hormones interact with muscles or metabolism in a way that would improve athletic performance. Some peptides communicate solely with other tissues. As an example, Melanotan is a peptide which causes the skin to produce more pigment and is not a drug likely to improve athletic prowess.

Four. Are peptides used in medicine?

Of the better understood peptide variants, one growth hormone related peptide - AOD-9604 - has recently found itself injected into the mainstream media - as well as Brownlow medallist Jobe Watson according to his recent admission. AOD-9604 was developed by researchers to combat obesity by increasing metabolic breakdown of stored fats and is likely to possess therapeutic potential in Australia’s obesity epidemic.

In response to the enormous threat presented by type-II diabetes in the Middle East, pipe-lined peptide products were revealed at the International Congress in Aesthetic and Anti-ageing Medicine (ICAAM) in Dubai last year. These peptide hormones are being developed not only to improve body composition but to restore insulin sensitivity – the key pathology implicated in the onset of type-II diabetes.

Five. Are peptides safe?

Although peptides are still accessible through countless “here-one-minute, gone-the-next” online stores, there are two serious issues that potentially endanger those entrusting these sites:

    According to a presentation by the TGA, many of the under-researched peptides being sold online have the potential to cause severe immune reactions and;
    Although some companies may be producing these products in the proper facilities, there are no guarantees or regulating bodies that ensure the products found online are legitimate, safe and free from bacterial contamination.

Legitimate pharmaceutical-grade peptides with proven efficacy and safety are slowly making their way to Australian pharmacies as a result of thorough clinical trials. However, it’s more than likely that your physician will always be the one to have the final say as to whether the potential benefits of these drugs outweigh the potential risks.

Monday, January 6, 2014

What is Melanotan and What does it do?

Melanotan-II was first created at The University of Arizona as a possible way to help people ward off skin cancer. Melanotan-II is formulated in a lab and is a reproduction of a hormone that human body naturally produces called melanocyte-stimulating hormone. This hormone helps the body’s natural pigmentation become active and produce tanned skin. It takes about two weeks for the skin to tan and the effects last only if the substance is administered regularly. After many studies, it was stated that the effects of the synthesized Melanotan-II injection did not last long enough, and the FDA, as well as many other countries medical approval systems denied Melanotan-II as being effective for tanning and cancer prevention. So, researchers decided to find another possible way of utilizing the formulated product.

Palatin Technologies jumped on the opportunity to discover new uses for the synthetic hormone and were able to distill another similar-like human hormone called Bremelanotide. Bremelanotide, while in its proper name, is still referred to as  Melanotan-II is now administered as an injection to produce erections in men with ED (erectile dysfunction), as well as for people who would like to have a tanned look. The results for men with erectile dysfunction are quite impressive. One study showed that seventeen out of twenty men, who were injected with Melanotan-II, became aroused and the average erection lasted about four hours and had a high rigidity. The hormone does not just produce erections, it also sustains sexual arousal and desire in men. Sounds like a winne

So, if you are looking to have longer, harder erection, while having a stronger sex drive, plus the effect of looking tan, then Melanotan-II is the drug for you. It is meant for men who have erectile dysfunction or a lower libido, so if you feel you could use a little more pep in your step Melanotan-II is the way to go.
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