GenezaMeds.com

GenezaMeds.com

Tuesday, June 24, 2014

Fat loss and muscle mass effects of CJC-1295

CJC-1295 was developed for clinical trials in the year 2000. The drug was originally synthesized to remove visceral fat deposits in AIDS patients. CJC 1295 was ultimately successful on all research subjects, as increasing the level of growth hormone in the body proved to increase fat loss.

Another very positive benefit of CJC-1295/CJC-1293 is its ability to promote slow wave sleep. Slow wave sleep is also known as deep sleep and is the portion of sleep responsible for the highest level of muscle growth and memory retention. SWS are decreased significantly in older adults and also with people who tend to exercise later in the evening.

This peptide has a benefit to side effect ratio that exceeds all others currently being legally sold and would make a great addition to ones training regimen or post cycle therapy.

CJC-1295 has the ability to make the body produce its own GH as compared to using synthetic HGH. GHRP-2 in conjunction with CJC-1295 is synergistic, amplifying the GH pulse considerably. Studies have shown that CJC-1295 also promotes slow-wave sleep, the kind of sleep responsible for muscle growth and increased memory retention.

There are three popular and clinically proven GHRH analogs on the market today, CJC-1293, CJC-1295, CJC-1295 DAC, and Sermorelin. CJC-1293 is a longer lasting peptide- it is sometimes also referred to as tetrasubstituted GRF(1-29) or Modified Sermorelin.

The half life of Research peptide CJC1295 is more desirable and establishes a significant enough of a GH pulse to increase IGF-1 levels and GH levels. However, it's pulsatile release is more of a sustained-consistent release that does not necessarily mimic that of the pituitary gland.

The CJC-1295 & the total 24 hour dosing of GHRP-6 together comprise a single comparison with exogenic GH administration.

Thursday, June 12, 2014

Four Kinds of Testosterone – Cypionate, Enanthate, Propionate, Suspension

The principal difference between these kinds of testosterone is duration of action.

There’s also some difference in the amount of actual testosterone contained per milligram of drug. In order of highest testosterone concentration to least-high but still high, the order is suspension, propionate, enanthate, and cypionate.

In practice however it's not important. Rarely does anyone account for this in deciding their testosterone dosage. It’s a point that may be glossed past with no problem.

The above is also the order of duration of action, from shortest to longest.

For practical purposes, testosterone cypionate and enanthate may be used fairly interchangeably. The half-life of enanthate is probably about 4-5 days, while that of cypionate is probably about a day longer. Accordingly, both of these clear the body relatively slowly at the end of a cycle, causing a relatively long period where levels are neither high enough to allow much if any further gains, yet not low enough to allow recovery.

Testosterone propionate has a much shorter half-life of probably only about 2 days. As a result, clearance of testosterone propionate is quick at the end of a cycle.

By half-life, is meant the time period in which levels of drug drop by 50%. For example, if a drug has a one day half-life, then after one day levels will have fallen to ½, after two days to ¼, after three days to รข…›, etc.

Testosterone suspension has a variable duration of action of at least several days and up to at least a week. The pattern in which levels drop, however, is different from those of drugs having a half-life. Instead, particles of drug slowly dissolve, and the particles slowly shrink. Release slows somewhat as the particles shrink and their surface area decreases. Any given particle will at some point disappear entirely. When nearly all have entirely dissolved, the duration of action of the suspension has ended.

Because of how this works, duration is dependent on particle size of the suspension. This is variable between products. Broadly speaking though, products which are milkier, which take longer to fall out of solution, and which go completely easily through the finest needle will have shorter duration of action than coarser products.

A good suspension of testosterone can be used similarly to testosterone propionate.

It's recommended to save the propionate and suspension for use at the end of the cycle, to enable faster transition from high levels allowing gains to low levels allowing recovery. There’s no value in spending an extended time after the last injection with levels still too high to allow recovery, yet not high enough to allow further gains. Actually, it’s not just that there’s no value, but a negative value: it impedes recovery.

Strategic use of propionate esters and suspension at the end of a cycle aids rapid recovery.

Tuesday, June 3, 2014

“Tren Cough” from Trenbolone Acetate

Trenbolone acetate has the unusual property of being irritating to at least some tissues. To the tongue, it’s very spicy. And if you have even a trace of it on your hands, don’t handle your meat or potatoes before washing it off thoroughly. It’s very irritating to them, should this be forgotten.

It is suspected that trenbolone acetate at very high concentration is also irritating to lung tissue.

Ordinarily, blood levels are nowhere near the level that produces tren cough. However, some individual injections may either introduce a small amount of oil directly into a very small blood vessel, or perhaps some trenbolone acetate enters immediately into the lymphatic system. The body, including the lungs, then experiences a very high level of it, and tren cough results.

Partly, whether tren cough occurs or not on a given injection is a matter of luck.

Another factor is the formulation of the injection. Higher concentration trenbolone acetate seems far more prone to causing the problem, and benzyl alcohol also seems to increase the prevalance.

To minimize the rate of tren cough, I’d stick with 50 mg/mL or at most 75 mg/mL, preferably with no benzyl alcohol. For 50 mg/mL, nothing is needed in the formulation except trenbolone acetate and vegetable oil or ethyl oleate; benzyl benzoate is optional. At 75 mg/mL, when not using benzyl acetate benzyl benzoate is mandatory. I suggest a 20% concentration of benzyl benzoate.

When tren cough does occur with a given injection, there’s nothing to do but tough it out. It always goes away relatively quickly. I’d say the worst I’ve experienced was no more than 90 seconds, and perhaps only ever one time has it gone past 60 seconds.