How To Prevent Estrogen Effects with GP Anastrozole by Geneza Pharmaceuticals

GP Anastrozole is an oral aromatase inhibitor manufactured by Geneza Pharmaceuticals. It was created for adjutant therapy of postmenopausal women with hormone receptor-positive early breast cancer. GP Anastrozole is a true aromatase inhibitor which works by blocking the aromatase enzyme in the body, thus limiting the amount of estrogen buildup that takes place.

Another use of anastrozole for men is to maintain a powerfully-built and bulky physique among bodybuilders, especially those who take anabolic steroids. One function of steroids is that it mimics the actions of naturally occurring testosterone, resulting in the increase of protein levels, muscle buildup, and strength improvement. Ironically, the excessive levels of testosterone and testosterone-like drugs signal the body to convert the male hormones into estradiol, which can lead to development of female features such as breasts and fat retention. Bodybuilders counter this hormone conversion by using anastrozole, but usage is often mishandled and may produce more adverse effects.

In studies that have been done, Anastrozole has been shown to reduce estrogen in the body by roughly 50%. This is a good balance for bodybuilders, because some estrogen is needed in order for the full anabolic benefits of the steroids being taken to be achieved.

It is wrong to think, however, that estrogen and its effects (particularly water and fat retention) are absolutely detrimental to bodybuilding. Remember that this hormone is also responsible for muscle strength and gains. Consequently, it minimizes the occurrence of injury as it improves the ability of muscle fibers to withstand contractile tension or stress. Notice that one of the side effects of Anastrozole use is the likely occurrence of fractures, a major drawback of this drug. This is because when Anastrozole effectively blocks the formation of estrogen, it effectively blocks the benefits of this hormone as well. This is why many still decide for estrogen receptor antagonists like Nolvadex and Clomid because these drugs allow some estrogen activity in the body.

Further, aromatase inhibitors like Anastrozole have the tendency to completely suppressed estrogen activity, including its positive effect on cholesterol levels in the body. Anastrozole is known to decrease HDL what is commonly known as the 'good' cholesterol. Typically, bodybuilders using GP Anastrozole will begin taking it the day they start their cycle, and will run it throughout the duration of steroid administration. It is also important to point out GP Anastrozole's ability to increase testosterone in the body. Some studies have shown that natural testosterone levels have increases as much as 60% after the use of this substance for 7 days. Because of this, bodybuilders find this drug extremely effective during PCT where as they are trying to elevate natural levels as much as possible in order to avoid a post cycle "crash".

Daily dosage for males is from 0.5mg to 3mg. For women, a maximum dosage of 1mg per day is enough to combat estrogenic side effects. Because Anastrozole has a short active life, dosages are usually taken two to six times a day at equal intervals. During PCT, athletes normally start with higher dosage then implement a progressive decrease in dosage. The PCT protocol typically runs for seven to 14 days. In clinical studies, it has been observed that a daily dose of 1 mg of this drug results to more than 80% of estrogen suppression.

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